Developed a custom, blood-free perfusion circuit specifically engineered for the fluid dynamics and metabolic requirements of a proprietary T3-hormone solution. Currently under experimental evaluation with clinical experts, this system completely replaces conventional blood-based perfusates. To support this architecture, we established novel clinical protocols dictating the perfusion mechanics and the physiological state of the solution. We integrated custom sensors, live data visualization, and an automated control system to continuously monitor and precisely regulate critical parameters such as flow, pressure, and temperature ensuring optimal organ viability in real-time.